Now what? With 2020 in the rearview mirror we break down the forces that will shape the trajectory of digital health over the next twelve months. We explore four themes that will impact digital health this year. To kick off the new year, we are reflecting on the profound impact that the last twelve months will have on the next twelve for digital health. Although 2020’s tumultuous events—a global pandemic and social and political tension—have not resolved, we’re encouraged by the opportunity we see for digital health in 2021. This trajectory is shaped by three forces: